| |
Academic Staff
Adjunct Staff
Research Staff
|
|
|
|
Academic Qualifications
|
| B.Sc. Pharm (Hons)
| |
University of Aberdeen,
UK |
| Ph.D.
| |
Dalhouse University,
Canada |
|
Dr Shabbir Moochhala graduated with
a BSc (with Honours) in Pharmacology from the University of
Aberdeen, UK, and obtained his PhD in Pharmacology at the
Dalhouse University, Canada. Between 1987 and 1992 he was
a Teaching Fellow in the Department of Pharmacology, National
University of Singapore. From 1992 to 1996 he was Research
Scientist in the Department of Surgery, Faculty of Medicine,
National University of Singapore, and his work included undertaking
and overseeing research projects, teaching and conducting
consultancy services. Dr Moochhala is currently Senior Research
Scientist and Head of Applied Physiology Branch at DMRI, and
an Honorary Fellow at the Department of Surgery at the National
University of Singapore . He has a wide range of research
interests, notably in Applied Physiology and Pharmacology.
His ongoing research work areas include Exercise Physiology,
Sleep/Wakefulness and Management, Thermal Physiology, Traumatology
and Wound Healing. In addition, Dr Moochhala is involved in
reviewing papers for various international and local journals,
as well as grant proposals for the National Medical Research
council.
|
| Research
Interests |
- Ergogenic Aids for Superior Performance
Ergogenic aids refer to techniques and substances used
for the purpose of enhancing performance. Our research
focuses on identifying and understanding muscle fatigue
and limiting physiological factors, predicting the capacity
to sustain work performance of various intensities, and
developing strategies using these ergogenic aids to acutely
enhance physical performance and improve physical training
methods. In addition we are currently involved in identifying
key intrinsic (immune and endocrine) factors that are
responsible for fatigue and infection development following
exercise, and are developing ways through pharmacological
or physiological means to alleviate these problems.
- Resuscitation Medicine Following Trauma
This area of research relates to major traumatic injury
and related stress that induces host defence mechanisms
that are associated with multisystem organ failure and
death. We are focusing on the pathophysiological sequelae
following trauma injury in relevant animal tissue preparations
and cell culture systems, and are also examining the role
of inflammatory mediators in trauma patients and their
ability to predict outcome in terms of morbidity and mortality.
Immunological and neurological alterations following hemorrhagic
shock in the rodent closed head injury model, as well
as the effects of pharmacological agents and conservative
fluid therapy are also under active study.
- Ballistic/Blast Injury
We are studying the effects of high and low velocity
ballistic trauma on the morphological, physiological and
immunological consequences of ballistic wounds, and the
effects of various interventional measures for altering
the outcome of such wounds. Animal models are employed
to study the cellular mechanisms that mediate the maintenance
of enduring neurological deficits following traumatic
brain injury. Our research topics include:
- Wound Injury and Repair
This research program focuses on the mechanisms of wounding
and wound repair. Both animal models as well as a human
skin culture model of wounding to study the molecular
and cellular biology of wounding are being developed,
and we are also looking into novel drug therapies to accelerate
healing and minimise scar formation. Specifically we have
developed and are studying
|
|
|
