Research Interests:
The Roles of Cytoskeletal Proteins in Tumour Biology
Gelsolin (an Actin-Binding Protein) in the Oncogenic Pathway
Academic Background:
2003 PhD (Biomedical Sciences), University of Edinburgh, United Kingdom.
1993 MBBS (Singapore)
Selected Publications:
B. Yan, F.M. Omar, K. Das, W.H. Ng, C. Lim, K. Shiuan, C.T. Yap, M. Salto-Tellez (2008). Characterization of Numb expression in astrocytomas. Neuropathology 2008, 28:479-484.
B. Yan1, C.T. Yap1, S. Wang, C.K. Lee, F.M. Omar, M. Salto-Tellez, M.P. Kumarasinghe (2008). Cofilin immunolabelling correlates with depth of invasion in gastrointestinal endocrine cell tumours. Acta histochemica, in press.
C.T. Yap, T.I. Simpson, T. Pratt, D.J. Price, S.K. Maciver (2005). The motility of glioblastoma tumour cells is modulated by intracecellular cofilin expression in a concentration-dependent manner. Cell Motility and the Cytoskeleton 2005 Jan20; 60(3):153-165.
Conference Papers:
E.H. Tan, Tay H.K., B.J. Yan, S. Koh, S.C. Hooi, M. Salto-Tellez, C.T. Yap (2007). Investigating the roles of gelsolin in the malignant progression of colorectal tumour cells. National Cancer Research Institute Proceedings (UK), 62.
S. Koh, X.L. Chen, S.K. Maciver, C.T. Yap (2007). Investigating the roles of cofilin in tumour cell-matrix adhesion and spreading. National Cancer Research Institute Proceedings (UK), 60.
C.T. Yap, V. Fotaki, T. I. Simpson, P. Zaki, D. J. Price, J. O. Mason (2003). An in vivo model to investigate the role of the transcription factor Gli3 in forebrain development. European Life Scientist Organisation Proceedings, 687.
V. Fotaki, C. Yap, T. I. Simpson, D. J. Price, J. O. Mason (2003). Investigating the role of Gli3 in development of the telencephalon using nested cre-loxP gene targeting. Heidelberg Mouse Molecular Genetics Proceedings.
C.T. Yap, T.I. Simpson, T. Pratt, L. Sharp, D.J. Price, S.K. Maciver (2002). Overexpression of cofilin in glioma tumours induces changes in cell motility. European Life Scientist Organisation Proceedings, 57.
C.T. Yap, T.I. Simpson, T. Pratt, L. Sharp, D.J. Price, S.K. Maciver (2001). The role of actin-binding proteins in human glioma tumours. British Societies for Developmental Biology and Cell Biology Proceedings, 57.
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