Research Interests:

Mechanism of oxysterol-induced cytotoxicity

Genes which affect susceptibility of cancer cells to cytotoxic drugs

Academic Background:

M.B.B.S, National University of Singapore

American Board of Internal Medicine, Board Certification in Endocrinology, 1981

FRCPC Internal Medicine, Royal College of Physicians and Surgeons, Canada 1976

Ph.D, Experimental Medicine, McGill University, Canada 1973

Selected Publications:

Peter L Hwang (1999) Defeats in apoptosis. In: Molecular Biology in Cancer Medicine, 2nd ed. pp. 133-145. Eds Kurzrock R and Talpaz M (Martin Dunitz).

Low YL and PL Hwang (1995) Lymphoma cells selected for resistance against the cytotoxic effect of oxygenated sterols are also resistant to nonsteroidal antiestrogens. Biochimica et  Biophysica Acta, 1269: 32-40.

Hwang PL, MY Shoon, YL Low, L Lin and EHL NG (1995) Inhibitors of protein and RNA synthesis block the cytotoxic effects of non-steroidal antiestrogens. Biochimica et  Biophysica Acta, 1266: 215-222

Hwang PLH (1991) Biological activities of oxygenated sterols: physiological and pathological implications. Bioassays, 13: 583-589.

Hwang PLH (1990) High-affinity binding sites for oxygenated sterols in rat liver microsomes: possible identity with antiestrogen binding sites. Biochimica et  Biophysica Acta, 1033: 154-161.