Research Interests:
Tumourimmunotherapy
Augmentation and Differentiation of Hematopoietic Stem Cells
Immunomodulation
Academic Background:
Postdoctoral Fellow, The Scripps Research Institute, 1989-1991
PhD, University of Wuerzburg, Germany, 1986-1989
Diploma, University of Regensburg, Germany, 1981-1986
Selected Publications:
Zhibo Wang, Clarice Chen, Sharon N Finger, Shaqireen D/O Kwajah M M, Manfred Jung, Herbert Schwarz, Nigel Swanson, Ricky R. Lareu, Michael Raghunath. SAHA- a potential epigenetic therapeutic agent for lung fibrosis. European Respiratory Journal. Accepted, 2009.
Elaine Thum, Zhe Shao and Herbert Schwarz (2008) CD137, implications in immunity and potential for therapy. Frontiers in Bioscience.
S1, 336-351, 2009.
Jiang D., Chen Y., and Schwarz H (2008) CD137 Induces Proliferation of Murine Hematopoietic Progenitor Cells and Differentiation to Macrophages. J. of Immunology. 181(6):3923-32.
Jiang D, PSE Yue, D Drenkard and H Schwarz (2008) Induction of proliferation and monocytic differentiation of human CD34+ cells by CD137 ligand signaling. Stem Cells, 26(9):2372-81.
Zhe S, S Feng, DR Koh and H Schwarz (2008) Characterisation of soluble murine CD137 and its association with Systemic Lupus. Molecular Immunology, 45(15):3990-9.
Lippert U, K Zachmann, DM Ferrari, H Schwarz, E Brunner, AH Latif, C Neumann and A Soruri (2008) CD137 ligand reverse signaling has multiple functions in human dendritic cells during an adaptive immune response. European J. of Immunology, 38:1024-1032.
Sollner L, Shaqireen D/O Kwajah MM, JT Wu and H Schwarz (2007) Signal transduction mechanisms of CD137 ligand in human monocytes. Cellular Signalling, 19: 1899-1908.
Drenkard D, FM Becke, J Langstein, T Spruss, LA Kunz-Schughart, TE Tan, YC Lim and H Schwarz (2007) CD137 is Expressed on Blood Vessel Walls at Sites of Inflammation and Enhances Monocyte Migratory Activity. Faseb Journal, 21(2): 456-463.
Yu Q, FY Yue, XX Gu, H Schwarz, CM Kovacs and MA Ostrowski (2006) OX40 ligation of CD4+ T cells enhances virus-specific CD8+ T cell memory responses independently of IL-2 and CD4+ T regulatory cell inhibition. J. of Immunology, 176(4): 2486-2495.
Ierna MX, HE Scales, H Schwarz, C Bunce, A McIlngorm, P Garside and CE Lawrence (2006) OX40 Interactions in Gastroentesinal Nematode Infection. Immunology. 117(1): 108-116.
Furtner M, RH Straub, S Kruger and H Schwarz (2005) Soluble CD137 is Increased in Sera of Leukemia and Lymphoma Patients. Leukemia, 19(5): 883-885.
Schwarz H (2005) Biological activities of reverse signal transduction through CD137 ligand. J. Leukocyte Biology. 77: 281-286.
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