Role of Proline Rich Acidic Protein and Heparan / Heparin Sulfate Interacting Protein in Colon Cancer Cell Proliferation

The 2 genes encoding the respective proteins are over-expressed in colorectal tumours compared to adjacent normal mucosa. Knock-downs and over-expression of the respective genes in colon cancer cell lines are performed to understand the function of the genes in cell proliferation.

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